Developmental changes in nephron number, proximal tubular length and superficial nephron glomerular filtration rate of rats.
نویسندگان
چکیده
منابع مشابه
Development of glomerular perfusion rate and nephron filtration rate in rats 17-60 days old.
The development of filtration rate and perfusion rate in superficial nephrons has been studied in 17- to 60-day-old rats with micropuncture and microsphere techniques. Recordings have also been made of total renal blood flow (RBF), cardiac output (CO), arterial blood pressure, and hematocrit. Sincle-nephron glomerular filtration rate (SNGFR) as well as glomerular perfusion rate (GPR) and RBF de...
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Sodium ferrocyanide was used to measure the intrarenal distribution of single nephron glomerular filtration rate (SNGFR) in remaining kidneys of dogs, 10 d after contralateral nephrectomy. It was first demonstrated that the renal function of both kidneys in situ was comparable. Following right nephrectomy, the urine volume, p-aminohippuric acid clearance, creatine clearance, osmolar clearance, ...
متن کاملDistal tubular feedback in the autoregulation of single nephron glomerular filtration rate.
Renal clearance and recollection micro-puncture experiments were conducted to evaluate the possible role of a distal tubular feedback mechanism in the phenomenon of renal autoregulation in dogs. Single nephron glomerular filtration rate (SNGFR) was measured from collection sites in both the proximal (proximal SNGFR) and distal tubules (distal SNGFR). Single nephron autoregulatory behavior was a...
متن کاملSingle-Nephron Glomerular Filtration Rate in Healthy Adults.
BACKGROUND The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single-nephron GFR assesses the function of individual nephrons. How the single-nephron GFR relates to demographic and clinical characteristics and kidney-biopsy findings in humans is unknown. METHODS We identified 1388 living kidney donors at the Mayo Clinic and the Cleveland Clinic who underwent a...
متن کاملSome artifacts in measuring single nephron glomerular filtration rate.
The existence of many artifacts in measuring single nephron glomerular filtration rate (SNGFR) by micropuncture technique has been pointedI out by several investigators. One of the more important sources of error is "retrograde contamination." This artifact was initially suggested by Rector and co-workers in 1 966 tnd(ler conclitions of partial uireteral obstrtuction( 1). Subse(quently Brenner ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1977
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1977.sp012061